Medical formulation

Posted on Jan 08, 2009 under xn--zqqs84h3is.com | edit
  • i have a list of ingredients for a quinine sulphate suspension, i need to make a solution/syrup 300mg per 5ml and another 600mg per 5ml and another 150mg/5ml. ingredients are quinine sulphate, cocoa powder,compound tragacanth powder, mehtyl and propyl hydroxybenzoates,syrup and vanilla essence. If you could help me out id appreciate ie


  • sorry if my question wasnt clear. im making a syrup and it needs to be of concentration 300 mg quinine sulfate powder per 5 ml with the above ingredients. i just want to know how much of each excipeient i need to add mainly to disguise the bitter taste and not to have added too much. im making up a 150 ml bottle and it needs to have as long a shelf life as possible. Im not sure whether or not i need a co solvelt to disolve the quinine sulfate ie alcohol and double strength chloroform water. also is it recommended to use an artificial sweetener such as sacharin


  • The list of ingredients will not help here. We need some more info that may be on the packet: If the suspension is ready to use, there should be a dose on the packet: eg contains 300mg per 5 mL. Then if this is the case, and you need to take 600mg of quinine sulphate, you can take 10ml of suspension. ( 300mg x 2 = 600 mg, 5mL x 2 = 10 mL needed) If it is a powder, it may ask you to add a certain amount of water to get the concentration required: eg, add 400 ml to get a suspension containing 300 mg/mL. You can then change the amount of water to add, or you can make it up as directed and change the ammount to take, as above.


  • Sorry I can't help you anymore, A compounding pharmacist may be able to help. here is an address for one in the US: http://www.villagedrug.com/ if you leave a message in the guestbook, they may help you.







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